In this paper we1 assess the potential for research on nonhuman animals to address questions about the phenomenology of painful experiences. Nociception, the basic capacity for sensing noxious stimuli, is widespread in the animal kingdom. Even rel- atively primitive animals such as leeches and sea slugs possess nociceptors, neurons that are functionally specialized for sensing noxious stimuli (Walters 1996). Vertebrate spinal cords play a sophisticated role in processing and modulating nociceptive signals, providing direct control of some motor responses to noxious (...) stimuli, and a basic capacity for Pavlovian and instrumental conditioning (Grau et al. 1990; Grau 2002). Higher brain systems provide additional layers of association, top-down control, and cognition. In humans, at least, these higher brain systems also give rise to the conscious experiences that are characteristic of pain. What can be said about the experiences of other animals who possess nervous systems that are similar but not identical to humans? (shrink)

Several well-known theodicies, whatever their merits, seem to make little sense of animal suffering. Here we argue that the problem of animal suffering has more layers than has generally been acknowledged in the literature and thus poses an even greater challenge to traditional Judeo-Christian Theism than is normally thought. However, the Neo-Cartesian (NC) defence would succeed in defanging this Expanded Problem of Animal Suffering. Several contemporary philosophers have suggested that recent evidence either supports the NC view or at least should (...) decrease our incredulity with respect to it. We discuss new evidence that undermines the NC position and thus reassert the gravity of the Expanded Problem. (shrink)

Several influential philosophers and scientists have advanced a framework, often called Neo-Cartesianism (NC), according to which animal suffering is merely apparent. Drawing upon contemporary neuroscience and philosophy of mind, Neo-Cartesians challenge the mainstream position we shall call Evolutionary Continuity (EC), the view that humans are on a nonhierarchical continuum with other species and are thus not likely to be unique in consciously experiencing negative pain affect. We argue that some Neo-Cartesians have misconstrued the underlying science or tendentiously appropriated controversial views (...) in the philosophy of mind. We discuss recent evidence that undermines the simple neuroanatomical structure-function correlation thesis that undergirds many Neo-Cartesian arguments, has an important bearing on the recent controversy over pain in fish, and places the underlying epistemology framing the debate between NC and EC in a new light that strengthens the EC position. (shrink)

As the above quote clearly highlights, it is the responsibility of researchers and research supervisors to be certain that their research staff and students assistants are very familiar with all of the ethical principles and current standards relevant to the research they are conducting. Indeed, they must take an active role in being certain that their research staff and students complete appropriate training in these ethical principles and standards, and how they apply them to the research context in which they (...) are working. This is especially important in areas in which there may be physical harm such as chronic pain research. During the past decade, there has been a great increase in research of chronic pain, with breakthroughs in better understanding its etiology, assessment, and treatment (1,2). Obviously, much of this research was conducted using humans and animals as subjects. As a consequence, there were a number of ethical issues that investigators have to be cognizant of when conducting their studies. In this chapter, we will discuss such ethical issues in three major areas: (i) laboratory research with human subjects; (ii) laboratory research with animals; and (iii) translating these laboratory research ndings to ‘‘real world’’ applications in the clinical treatment arena. (shrink)